Submissions from 2011
The Immunosuppressive Activity of Polymeric Micellar Formulation of Cyclosporine A: In Vitro and In Vivo Studies, Samar Hamdy, Azita Haddadi, Anooshirvan Shayeganpour, Aws Alsamsan, Hamidreza Montazeri Aliabadi, and Afsaneh Lavasanifar
Multimodal Spectral Imaging of Cells using a Transmission Diffraction Grating on a Light Microscope, Dragan Isailovic, Yang Xu, Tyler Copus, Suraj Saraswat, and Surya M. Nauli
Substituted Coumarin Derivatives: Synthesis and Evaluation of Antiproliferative and Src Kinase Inhibitory Activities, Abha Kathuria, Sarah Jalal, Rakesh Tiwari, Amir Nasrolahi Shirazi, Shilpi Gupta, Shiv Kumar, Keykavous Parang, and Sunil K. Sharma
Endothelin, Yoshifumi Kawanabe and Surya M. Nauli
Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole Conjugates and Evaluation of Their Src Kinase Inhibitory and Anticancer Activities, Anil Kumar, Israr Ahmad, Bhupender S. Chhikara, Rakesh Tiwari, Deendayal Mandal, and Keykavous Parang
Click Chemistry Inspired One-Pot Synthesis of 1, 4-disubstituted 1, 2, 3-triazoles and Their Src Kinase Inhibitory Activity, Dalip Kumar, V. Buchi Reddy, Anil Kumar, Deendayal Mandal, Rakesh Tiwari, and Keykavous Parang
Neuroprotective Effects of Bilobalide are Accompanied by a Reduction of Ischemia-Induced Glutamate Release in vivo, Dorothee Lang, Cornelia Kiewert, Alexander Mdzinarishvili, Tina Maria Schwarzkopf, Rachita K. Sumbria, Joachim Hartmann, and Jochen Klein
Efficacious and Safe Tissue-Selective Controlled Gene Therapy Approaches for the Cornea, Rajiv R. Mohan, Sunilima Sinha, Ashish Tandon, Rangan Gupta, Jonathan C. K. Tovey, and Ajay Sharma
Significant Inhibition of Corneal Scarring in vivo with Tissue-Selective, Targeted AAV5 Decorin Gene Therapy, Rajiv R. Mohan, Ashish Tandon, Ajay Sharma, John W. Cowden, and Jonathan C. K. Tovey
Targeted Decorin Gene Therapy Delivered with Adeno-Associated Virus Effectively Retards Corneal Neovascularization in vivo, Rajiv R. Mohan, Jonathan C. K. Tovey, Ajay Sharma, Gregory S. Schultz, John W. Cowden, and Ashish Tandon
Editorial Focus: An ACE Inhibitor Improves Vascular Outcomes in a PKD Model, Surya M. Nauli
The Mechanosensory Role of Primary Cilia in Vascular Hypertension, Surya M. Nauli, Xingjian Jin, and Beerend P. Hierck
Cumulative Clinical Experience from Over a Decade of Use of Levofloxacin in Community Acquired Pneumonia; Critical Appraisal and Role in Therapy, Ayman M. Noreddin, Walid F. Elkhatib, Kenji M. Cunnion, and George G. Zhanel
Improved Inactivation Effect of Bacteria Fabrication of Mesoporous Anatase Films with Fine Ag Nanoparticles Prepared by Coaxial Vacuum Arc Deposition, Hamid Oveisi, Simin Rahighi, Xiangfen Jiang, Yoshiaki Agawa, Ali Beitollahi, Soichi Wakatsuki, and Yusuke Yamauchi
3-Substitued Indoles: One Pot Synthesis and Evaluation of Anticancer and Src Kinase Inhibitory Activities, V. Kameshwara Rao, Bhupender S. Chhikara, Amir Nasrolahi Shirazi, Rakesh Tiwari, Keykavous Parang, and Anil Kumar
Comparative Pharmacodynamics of Ceftobiprole, Daptomycin, Linezolid, Telavancin, Tigecycline, and Vancomycin in the Treatment of Methicillin Resistant Staphylococcus aureus: A Monte Carlo Simulation Analysis, Ahmed H. Salem, Ehab A. Noreddin, George G. Zhanel, and Ayman M. Noreddin
Polyethylenimine-Conjugated Gold Nanoparticles: Gene Transfer Potential and Low Toxicity in the Cornea, Ajay Sharma, Ashish Tandon, Jonathan C. K. Tovey, Rangan Gupta, J. David Robertson, Jennifer A. Fortune, Alexander M. Klibanov, John W. Cowden, Frank G. Rieger, and Rajiv R. Mohan
Thyroglobulin Gene Mutations in Congenital Hypothyroidism, Héctor M. Targovnik, Cintia E. Citterio, and Carolina M. Rivolta
Co-Creation of Experiential Qualities, Vuk Uskoković
Turning the Paradigm Upside Down: Postdocs as Principal Investigators’ Mentors, Vuk Uskoković
Hydrolysis of Amelogenin by Matrix Metalloprotease-20 Accelerates Mineralization in vitro, Vuk Uskoković, Feroz Khan, Haichuan Liu, Halina Ewa Witkowska, Li Zhu, Wu Li, and Stefan Habelitz
Biomimetic Precipitation of Uniaxially Grown Calcium Phosphate Crystals from Full-Length Human Amelogenin Sols, Vuk Uskoković, Wu Li, and Stefan Habelitz
Dynamic Light Scattering and Zeta Potential of Colloidal Mixtures of Amelogenin and Hydroxyapatite in Calcium and Phosphate Rich Ionic Milieus, Vuk Uskoković, Roselyn Odsinada, Sonia Djordjevic, and Stefan Habelitz
Extrapolating Strategies for the Scientific and Technological Development of Underdeveloped Societies from the Examples of South Korea, Slovenia and Serbia, Vuk Uskoković and Dragan Uskoković
Antivirulence Potential of TR-700 and Clindamycin on Clinical Isolates of Staphylococcus aureus Producing Phenol-Soluble Modulins, Jason Yamaki, Timothy Synold, and Annie Wong-Beringer
Ceftaroline Pharmacodynamic Activity versus Community-Associated and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus, Heteroresistant Vancomycin-Intermediate S. aureus, Vancomycin-Intermediate S. aureus and Vancomycin-Resistant S. aureus Using an In Vitro Model, George G. Zhanel, Emma Rossnagel, Kim Nichol, Lauren Cox, James A. Karlowsky, Sheryl Zelenitsky, Ayman M. Noreddin, and Daryl J. Hoban
Altered Self-Assembly and Apatite Binding of Amelogenin Induced by N-terminal Proline Mutation, Li Zhu, Vuk Uskoković, Thuan Le, Pamela DenBesten, Yulei Huang, Stefan Habelitz, and Wu Li
Submissions from 2010
Synthesis, Antiviral and Contraceptive Activities of Nucleoside-Sodium Cellulose Sulfate Acetate and Succinate Conjugates, Hitesh K. Agarwal, Anil Kumar, Gustavo F. Doncel, and Keykavous Parang
Synthesis of Nucleoside 5′-O-α,β-methylene-β-triphosphates and Evaluation of Their Potency Towards Inhibition of HIV-1 Reverse Transcriptase, Yousef Ahmadibeni, Chandravanu Dash, M. J. Hanley, S. F. J. Le Grice, Hitesh K. Agarwal, and Keykavous Parang
5¢-O-b,g-Methylenetriphosphate Derivatives of Nucleoside, Yousef Ahmadibeni, Chandravanu Dash, S. F. J. Le Grice, and Keykavous Parang
Isolation and Cultivation of Equine Corneal Keratocytes, Fibroblasts and Myofibroblasts, Dylan G. Buss, Elizabeth A. Giuliano, Ajay Sharma, and Rajiv R. Mohan
Efficacy and Safety of Mitomycin C as an Agent to Treat Corneal Scarring in Horses Using an in vitro Model, Dylan G. Buss, Ajay Sharma, Elizabeth A. Giuliano, and Rajiv R. Mohan
Gene Delivery in the Equine Cornea: A Novel Therapeutic Strategy, Dylan G. Buss, Ajay Sharma, Elizabeth A. Giuliano, and Rajiv R. Mohan
Development of Cytarabine Prodrugs and Delivery Systems for Leukemia Treatment, Bhupender S. Chhikara and Keykavous Parang
Intravenous Artesunate for Severe Malaria, Karl M. Hess, Jeffery A. Goad, and Paul M. Arguin
Selective Binding of Linear Ubiquitin Chains to NEMO in NF-κB Activation, Fumiyo Ikeda, Simin Rahighi, Soichi Wakatsuki, and Ivan Dikic
In Vitro Release of Indian Penny Wort, Walnut, and Turmeric from Topical Preparations Using Two Different Types of Membranes, Sonia Khiljee, Nisar Ur Rehman, Muhammad Khan Sarfaz, Hamidreza Montazeri Aliabadi, Tanzila Khiljee, and Raimar Löbenberg
Fibroblast Specific Expression of AC6 Enhances ß-Adrenergic and Prostacyclin Signaling and Blunts Bleomycin-Induced Pulmonary Fibrosis, Xiaoqiu Liu, Shu Qiang Sun, Muthusamy Thangavel, Joseph Kaminsky, Joseph Kaminsky, Louisa Balazs, and Rennolds S. Ostrom
Vector Delivery Technique Affects Gene Transfer in the Cornea in vivo, Rajiv R. Mohan, Ajay Sharma, Tyler C. Cebulko, and Ashish Tandon
Good Research Practices for Measuring Drug Costs in Cost-Effectiveness Analyses: Medicare, Medicaid and Other US Government Payers Perspectives: The ISPOR Drug Cost Task Force Report—Part IV, C. Daniel Mullins, Brian Seal, Enrique Seoane-Vazquez, Jayashri Sankaranarayanan, Carl V. Asche, Ravishankar Jayadevappa, Won Chan Lee, Dorothy K. Romanus, Junling Wang, Joel W. Hay, and Jim Smeeding
A Comparative Study of Embedded and Anesthetized Zebrafish in Vivo on Myocardiac Calcium Oscillation and Heart Muscle Contraction, Brian S. Muntean, Christine M. Horvat, James H. Behler, Wissam A. AbouAlaiwi, Andromeda M. Nauli, Frederick E. Williams, and Surya M. Nauli
Impaired M3 and Enhanced M2 Muscarinic Receptor Contractile Function in a Streptozotocin Model of Mouse Diabetic Urinary Bladder, K. J. Pak, Rennolds S. Ostrom, M. Matsui, and F. J. Ehlert
The M2 Muscarinic Receptor Inhibits the Development of Streptozotocin-Induced Neuropathy of Mouse Urinary Bladder, K. J. Pak, Rennolds S. Ostrom, M. Matsui, and F. J. Ehlert
Plasma Pharmacokinetics and Tissue Disposition of Novel Dextran- Methylprednisolone Conjugates with Peptide Linkers in Rats, Suman Penugonda, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar
Failure to ubiquitinate c-Met Leads to Hyperactivation of mTOR Signaling in a Mouse Model of Autosomal Dominant Polycystic Kidney Disease, Shan Qin, Mary Taglienti, Surya M. Nauli, Leah Contrino, Ayumi Takakura, Jing Zhou, and Jordan A. Kreidberg
Hypertension in Autosomal Dominant Polycystic Kidney Disease: A Clinical and Basic Science Perspective, Shobha Ratnam and Surya M. Nauli
Practice Patterns for Antibiotic De-escalation in Culture-Negative Healthcare-Associated Pneumonia, M. Schlueter, C. James, A. Dominguez, Laura V. Tsu, and G. Seymann
AAV Serotype Influences Gene Transfer in Corneal Stroma in vivo, Ajay Sharma
Localization of Angiotensin Converting Enzyme in Rabbit Cornea and Its Role in Controlling Corneal Angiogenesis in vivo, Ajay Sharma, Daniel I. Bettis, John W. Cowden, and Rajiv R. Mohan
"Transduction Efficiency of AAV 2/6, 2/8 and 2/9 Vectors for Delivering Genes in Human Corneal Fibroblasts ", Ajay Sharma, Arkasubhra Ghosh, Eric T. Hansen, Jason M. Newman, and Rajiv R. Mohan
AAV Serotype Influences Gene Transfer in Corneal Stroma in vivo, Ajay Sharma, Jonathan C. K. Tovey, Arkasubhra Ghosh, and Rajiv R. Mohan
Acute Depression of Energy Metabolism After Microdialysis Probe Implantation is Distinct from Ischemia-Induced Changes in Mouse Brain, Rachita K. Sumbria, Jochen Klein, and Ulrich Bickel
Polystyrene-Supported Aluminum Chloride as an Efficient and Reusable Catalyst for Condensation of Indole with Various Carbonyl Compounds, Bahman Tamami, Amir Nasrolahi Shirazi, and Kaveh Parvanak Borujeni
Role of Transforming Growth Factor Beta in Corneal Function, Biology and Pathology, Ashish Tandon, Jonathan C. K. Tovey, Ajay Sharma, Rangan Gupta, and Rajiv R. Mohan
Synthesis and Evaluation of Conformationally Constrained Peptide Analogues as the Src SH3 Domain Binding Ligands, Rakesh Tiwari, Alex Brown, Seetha Narramaneni, Gongqin Sun, and Keykavous Parang
HCMV pUS28 Initiates Pro-Migratory Signaling via Activation of Pyk2 Kinase, Jennifer Totonchy, Susan Varnum, Ryan Melnychuk, Patricia Smith, Ljiliana Pasa-Tolic, Janani I. Shutthanadan, and Daniel N. Streblow
Major Challenges for the Modern Chemistry in Particular and Science in General, Vuk Uskoković
Morphological Study of Emulsion-Assisted Cholesterol Precipitation Processes, Vuk Uskoković
Prospects and Pits on the Path of Biomimetics: The Case of Tooth Enamel, Vuk Uskoković
The Metaphorical Model: The Bridge between Science and Religion, Vuk Uskoković
Nanotechnology in Dental Sciences: Moving Towards a Finer Way of Doing Dentistry, Vuk Uskoković and Luiz Eduardo Bertassoni
Zeta-Potential and Particle Size Analysis of Recombinant Human Amelogenins, Vuk Uskoković; Z. Castiglione; P. Cubas; L. Zhu; W, Li; and S. Habelitz
Strategies for the Scientific Progress of the Developing Countries in the New Millennium: The Case of Serbia in Comparison with Slovenia and South Korea, Vuk Uskoković, Milica Ševkušić, and Dragan P. Uskoković
Nanosized Hydroxyapatite and Other Calcium Phosphates: Chemistry of Formation and Application as Drug and Gene Delivery Agents, Vuk Uskoković and Dragan Uskoković
Disparity Implications of Medicare Eligibility Criteria for Medication Therapy Management Services, Junling Wang, C. Daniel Mullins, Lawrence M. Brown, Ya-Chen Tina Shih, Samuel Dagogo-Jack, Song Hee Hong, and William C. Cushman
Submissions from 2009
Primary Cilia: Highly Sophisticated Biological Sensors, Wissam A. AbouAlaiwi, Shao T. Lo, and Surya M. Nauli
Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades, Wissam A. AbouAlaiwi, Maki Takahashi, Blair Mell, Thomas J. Jones, Shobha Ratnam, Robert J. Kolb, and Surya M. Nauli
Synthesis of Nucleoside Mono-, Di-, and Triphosphoramidates from Solid-Phase cyclo Saligenyl Phosphitylating Reagents, Yousef Ahmadibeni, Rakesh Tiwari, Gongqin Sun, and Keykavous Parang
The Proteolytic Stability and Cytotoxicity Studies of l‐Aspartic Acid and l‐Diaminopropionic Acid derived β‐Peptides and a Mixed α/β‐Peptide, Sahar Ahmed and Kamaljit Kaur
Rat Cytomegalovirus Infection Depletes MHC II in Bone Marrow Derived Dendritic Cells, Carmen C. Baca Jones, Craig N. Kreklywich, Ilhem Messaoudi, Jennifer Totonchy, Erin McCartney, Susan L. Orloff, Jay A. Nelson, and Daniel N. Streblow
The First Total Synthesis of (±)-4-methoxydecanoic Acid: A Novel Antifungal Fatty Acid, Nestor Carballeira, Carlos Miranda, and Keykavous Parang
Novel Approach Against Central Venous Catheter Associated Infection with Acinetobacter baumannii Biofilm, Walid Elkhatib and Ayman M. Noreddin
The Guinea Pig Ileum Lacks the Direct, High-Potency, M2-Muscarinic, Contractile Mechanism of the Mouse Ileum, Michael T. Griffin, Minoru Matsui, Rennolds S. Ostrom, and Frederick J. Ehlert
Isoniazid Completion Rates for Latent Tuberculosis Infection Among College Students Managed by a Community Pharmacist, Karl M. Hess, Jeffery A. Goad, Joanne Wu, and Kathleen Johnson
Eugenia jambolana Lam. Berry Extract Inhibits Growth and Induces Apoptosis of Human Breast Cancer but Not Non-Tumorigenic Breast Cells, Liya Li, Lynn S. Adams, Caroline Killian, Aftab Ahmed, and Navindra P. Seeram
Pharmacodynamic Target Attainment Potential of Azithromycin, Clarithromycin and Telithromycin in Serum and Epithelial Lining Fluid (ELF) of Community Acquired Pneumonia (CAP) Patients with Penicillin-Susceptible, Intermediate and Resistant Streptococcus pneumoniae, Ayman M. Noreddin, Walid El-Khatib, Jason Aolie, Ahmed H. Salem, and George G. Zhanel
Updated Guidelines for Manuscripts Describing Instructional Design and Assessment: The IDEAS Format, Therese Poirier, Michael Crouch, George MacKinnon, Reza Mehvar, and Mary Monk-Tutor
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation, Simin Rahighi, Fumiyo Ikeda, Masato Kawasaki, Masato Akutsu, Nobuhiro Suzuki, Ryuichi Kato, Tobias Kensche, Tamami Uejima, Stuart Bloor, David Komander, Felix Randow, Soichi Wakatsuki, and Ivan Dikic
Provision of Health Care Services in Canada: Challenges and Opportunities, Rosa Rodriguez-Monguio, Enrique Seoane-Vazquez, and Fernando Antoñanzas Villar
Trichostatin A Inhibits Corneal Haze in vitro and in vivo, Ajay Sharma, Maneesh M. Mehan, Sunilima Sinha, John W. Cowden, and Rajiv R. Mohan
Localization and Coupling of Adenylyl Cyclase Isoforms 2, 3 and 6 With G Protein-Coupled Receptors in Mouse Bronchial Smooth Muscle Cells, Muthusamy Thangavel, Piyatilake Adris, and Rennolds S. Ostrom
The C1 and C2 Domains Target Human Type 6 Adenylyl Cyclase to Lipid Rafts and Caveolae, Muthusamy Thangavel, Xiaoqiu Liu, Shu Qiang Sun, Joseph Kaminsky, and Rennolds S. Ostrom
Differential Ligand Binding to a Human Cytomegalovirus Chemokine Receptor Determines Cell Type-Specific Motility, Jennifer Totonchy, Ryan Melnychuk, Patricia P. Smith, Joshua Powell, Laurel Hall, Victor R. DeFilippis, Klaus Fruh, Martine Smit, David D. Schlaepfer, Jay A. Nelson, and Daniel N. Streblow
Human Cytomegalovirus US28: A Functionally Selective Chemokine Binding Receptor, Jennifer Totonchy, Jay A. Nelson, and Daniel N. Streblow
A Collection of Micrographs: Where Science and Art Meet, Vuk Uskoković
Challenges for the Modern Science in its Descend Towards Nano Scale, Vuk Uskoković
New Dosing Schedules of Dasatinib for CML and Adverse Event Management, Siu Fun Wong
CD82 Endocytosis Reveals Cholesterol-Dependent Reorganization of Tetraspanin-Enriched Microdomains and Lipid Rafts, Congfeng Xu, Yanhui H. Zhang, Muthusamy Thangavel, Mekel M. Richardson, Lu Liu, Bin Zhou, Yi Zheng, Rennolds S. Ostrom, and Xin A. Zhang
The Complete Genome of Teredinibacter turnerae T7901: An Intracellular Endosymbiont of Marine Wood-Boring Bivalves (Shipworms), Joyce C. Yang, Ramana Madapu, A. Scott Durkin, Nathan A. Ekborg, Chandra S. Pedamallu, Jessica B. Hostetler, Diana Radune, Bradley S. Toms, Bernard Henrissat, Pedro M. Coutinho, Sandra Schwarz, Lauren Field, Amaro E. Trindade-Silva, Carlos A. G. Soares, Sherif Elshahawi, Amro Hanora, Eric W. Schmidt, Martha G. Haygood, Joanos Posfai, Jack Benner, Catherine Madinger, John Nove, Brian Anton, Kshitiz Chaudhary, Jeremy Foster, Alex Holman, Sanjay Kumar, Philip A. Lessard, Yvette A. Luyten, Barton Slatko, Nicole Wood, Bo Wu, Max Teplitski, Joseph D. Mougous, Naomi Ward, Jonathan A. Eisen, Jonathan H. Badger, and Daniel L. Distel
Synthesis and Evaluation of Phosphopeptides Containing Iminodiacetate Groups as Binding Ligands of the Src SH2 Domain, Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Joel R. Morgan, Absar Faruqui, Kezhen Huang, Gongqin Sun, John A. Zebala, and Keykavous Parang
Pharmacodynamic Activity of Ceftobiprole Compared with Vancomycin versus Methicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Intermediate Staphylococcus aureus (VISA) and Vancomycin-Resistant Staphylococcus aureus (VRSA) Using an In Vitro Model, George G. Zhanel, Dylan Voth, Kim Nichol, James A. Karlowsky, Ayman M. Noreddin, and Daryl J. Hoban
Liquid Chromatography-Tandem Mass Spectrometry for the Determination of Methylprednisolone in Rat Plasma and Liver After Intravenous Administration of Its Liver-Targeted Dextran Prodrug, Shuang-Qing Zhang, Helen R. Thorsheim, Suman Penugonda, Venkateswaran C. Pillai, Quentin R. Smith, and Reza Mehvar
Submissions from 2008
Symmetrical Dinucleosides, Yousef Ahmadibeni and Keykavous Parang
Helical Peptides Derived from Lactoferrin Bind Hepatitis C Virus Envelope Protein E2, Reem Beleid, Donna Douglas, Norman Kneteman, and Kamaljit Kaur
Zoledronic Acid Markedly Improves Bone Mineral Density for Patients with Monoclonal Gammopathy of Undetermined Significance and Bone Loss, James R. Berenson, Ori Yellin, Ralph V. Boccia, Marshall Flam, Siu Fun Wong, Olcay Batuman, Mehdi M. Moezi, Donald Woytowitz, Herbert Duvivier, Youram Nassir, and Regina A. Swift
A High-Throughput In Vitro Model Illustrating Potential Microbiologocal Interactions During Treatment of Pseudomonas aeroginosa Biofilm Associated Infections, Walid Elkhatib, Virginia Haynes, and Ayman M. Noreddin
Right-handed 14-Helix in β3-Peptides from L-Aspartic Acid Monomers, Kamaljit Kaur, Tara Sprules, Wael Soliman, Reem Beleid, and Sahar Ahmed
Ciliary Dysfunction in Polycystic Kidney Disease: An Emerging Model with Polarizing Potential, Robert J. Kolb and Surya M. Nauli
Fibroblast-Specific Expression of Adenylyl Cyclase 6 Reduces Myofibroblast Differentiation and Protects Against Bleomycin-Induced Pulmonary Fibrosis, Xiaoqiu Liu, Fengying Li, and Rennolds S. Ostrom