Submissions from 2009
Primary Cilia: Highly Sophisticated Biological Sensors, Wissam A. AbouAlaiwi, Shao T. Lo, and Surya M. Nauli
Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades, Wissam A. AbouAlaiwi, Maki Takahashi, Blair Mell, Thomas J. Jones, Shobha Ratnam, Robert J. Kolb, and Surya M. Nauli
Synthesis of Nucleoside Mono-, Di-, and Triphosphoramidates from Solid-Phase cyclo Saligenyl Phosphitylating Reagents, Yousef Ahmadibeni, Rakesh Tiwari, Gongqin Sun, and Keykavous Parang
The Proteolytic Stability and Cytotoxicity Studies of l‐Aspartic Acid and l‐Diaminopropionic Acid derived β‐Peptides and a Mixed α/β‐Peptide, Sahar Ahmed and Kamaljit Kaur
Rat Cytomegalovirus Infection Depletes MHC II in Bone Marrow Derived Dendritic Cells, Carmen C. Baca Jones, Craig N. Kreklywich, Ilhem Messaoudi, Jennifer Totonchy, Erin McCartney, Susan L. Orloff, Jay A. Nelson, and Daniel N. Streblow
The First Total Synthesis of (±)-4-methoxydecanoic Acid: A Novel Antifungal Fatty Acid, Nestor Carballeira, Carlos Miranda, and Keykavous Parang
Novel Approach Against Central Venous Catheter Associated Infection with Acinetobacter baumannii Biofilm, Walid Elkhatib and Ayman M. Noreddin
The Guinea Pig Ileum Lacks the Direct, High-Potency, M2-Muscarinic, Contractile Mechanism of the Mouse Ileum, Michael T. Griffin, Minoru Matsui, Rennolds S. Ostrom, and Frederick J. Ehlert
Isoniazid Completion Rates for Latent Tuberculosis Infection Among College Students Managed by a Community Pharmacist, Karl M. Hess, Jeffery A. Goad, Joanne Wu, and Kathleen Johnson
Eugenia jambolana Lam. Berry Extract Inhibits Growth and Induces Apoptosis of Human Breast Cancer but Not Non-Tumorigenic Breast Cells, Liya Li, Lynn S. Adams, Caroline Killian, Aftab Ahmed, and Navindra P. Seeram
Pharmacodynamic Target Attainment Potential of Azithromycin, Clarithromycin and Telithromycin in Serum and Epithelial Lining Fluid (ELF) of Community Acquired Pneumonia (CAP) Patients with Penicillin-Susceptible, Intermediate and Resistant Streptococcus pneumoniae, Ayman M. Noreddin, Walid El-Khatib, Jason Aolie, Ahmed H. Salem, and George G. Zhanel
Updated Guidelines for Manuscripts Describing Instructional Design and Assessment: The IDEAS Format, Therese Poirier, Michael Crouch, George MacKinnon, Reza Mehvar, and Mary Monk-Tutor
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation, Simin Rahighi, Fumiyo Ikeda, Masato Kawasaki, Masato Akutsu, Nobuhiro Suzuki, Ryuichi Kato, Tobias Kensche, Tamami Uejima, Stuart Bloor, David Komander, Felix Randow, Soichi Wakatsuki, and Ivan Dikic
Provision of Health Care Services in Canada: Challenges and Opportunities, Rosa Rodriguez-Monguio, Enrique Seoane-Vazquez, and Fernando Antoñanzas Villar
Trichostatin A Inhibits Corneal Haze in vitro and in vivo, Ajay Sharma, Maneesh M. Mehan, Sunilima Sinha, John W. Cowden, and Rajiv R. Mohan
Localization and Coupling of Adenylyl Cyclase Isoforms 2, 3 and 6 With G Protein-Coupled Receptors in Mouse Bronchial Smooth Muscle Cells, Muthusamy Thangavel, Piyatilake Adris, and Rennolds S. Ostrom
The C1 and C2 Domains Target Human Type 6 Adenylyl Cyclase to Lipid Rafts and Caveolae, Muthusamy Thangavel, Xiaoqiu Liu, Shu Qiang Sun, Joseph Kaminsky, and Rennolds S. Ostrom
Differential Ligand Binding to a Human Cytomegalovirus Chemokine Receptor Determines Cell Type-Specific Motility, Jennifer Totonchy, Ryan Melnychuk, Patricia P. Smith, Joshua Powell, Laurel Hall, Victor R. DeFilippis, Klaus Fruh, Martine Smit, David D. Schlaepfer, Jay A. Nelson, and Daniel N. Streblow
Human Cytomegalovirus US28: A Functionally Selective Chemokine Binding Receptor, Jennifer Totonchy, Jay A. Nelson, and Daniel N. Streblow
A Collection of Micrographs: Where Science and Art Meet, Vuk Uskoković
Challenges for the Modern Science in its Descend Towards Nano Scale, Vuk Uskoković
New Dosing Schedules of Dasatinib for CML and Adverse Event Management, Siu Fun Wong
CD82 Endocytosis Reveals Cholesterol-Dependent Reorganization of Tetraspanin-Enriched Microdomains and Lipid Rafts, Congfeng Xu, Yanhui H. Zhang, Muthusamy Thangavel, Mekel M. Richardson, Lu Liu, Bin Zhou, Yi Zheng, Rennolds S. Ostrom, and Xin A. Zhang
The Complete Genome of Teredinibacter turnerae T7901: An Intracellular Endosymbiont of Marine Wood-Boring Bivalves (Shipworms), Joyce C. Yang, Ramana Madapu, A. Scott Durkin, Nathan A. Ekborg, Chandra S. Pedamallu, Jessica B. Hostetler, Diana Radune, Bradley S. Toms, Bernard Henrissat, Pedro M. Coutinho, Sandra Schwarz, Lauren Field, Amaro E. Trindade-Silva, Carlos A. G. Soares, Sherif Elshahawi, Amro Hanora, Eric W. Schmidt, Martha G. Haygood, Joanos Posfai, Jack Benner, Catherine Madinger, John Nove, Brian Anton, Kshitiz Chaudhary, Jeremy Foster, Alex Holman, Sanjay Kumar, Philip A. Lessard, Yvette A. Luyten, Barton Slatko, Nicole Wood, Bo Wu, Max Teplitski, Joseph D. Mougous, Naomi Ward, Jonathan A. Eisen, Jonathan H. Badger, and Daniel L. Distel
Synthesis and Evaluation of Phosphopeptides Containing Iminodiacetate Groups as Binding Ligands of the Src SH2 Domain, Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Joel R. Morgan, Absar Faruqui, Kezhen Huang, Gongqin Sun, John A. Zebala, and Keykavous Parang
Pharmacodynamic Activity of Ceftobiprole Compared with Vancomycin versus Methicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Intermediate Staphylococcus aureus (VISA) and Vancomycin-Resistant Staphylococcus aureus (VRSA) Using an In Vitro Model, George G. Zhanel, Dylan Voth, Kim Nichol, James A. Karlowsky, Ayman M. Noreddin, and Daryl J. Hoban
Liquid Chromatography-Tandem Mass Spectrometry for the Determination of Methylprednisolone in Rat Plasma and Liver After Intravenous Administration of Its Liver-Targeted Dextran Prodrug, Shuang-Qing Zhang, Helen R. Thorsheim, Suman Penugonda, Venkateswaran C. Pillai, Quentin R. Smith, and Reza Mehvar
Submissions from 2008
Symmetrical Dinucleosides, Yousef Ahmadibeni and Keykavous Parang
Helical Peptides Derived from Lactoferrin Bind Hepatitis C Virus Envelope Protein E2, Reem Beleid, Donna Douglas, Norman Kneteman, and Kamaljit Kaur
Zoledronic Acid Markedly Improves Bone Mineral Density for Patients with Monoclonal Gammopathy of Undetermined Significance and Bone Loss, James R. Berenson, Ori Yellin, Ralph V. Boccia, Marshall Flam, Siu Fun Wong, Olcay Batuman, Mehdi M. Moezi, Donald Woytowitz, Herbert Duvivier, Youram Nassir, and Regina A. Swift
A High-Throughput In Vitro Model Illustrating Potential Microbiologocal Interactions During Treatment of Pseudomonas aeroginosa Biofilm Associated Infections, Walid Elkhatib, Virginia Haynes, and Ayman M. Noreddin
Right-handed 14-Helix in β3-Peptides from L-Aspartic Acid Monomers, Kamaljit Kaur, Tara Sprules, Wael Soliman, Reem Beleid, and Sahar Ahmed
Ciliary Dysfunction in Polycystic Kidney Disease: An Emerging Model with Polarizing Potential, Robert J. Kolb and Surya M. Nauli
Fibroblast-Specific Expression of Adenylyl Cyclase 6 Reduces Myofibroblast Differentiation and Protects Against Bleomycin-Induced Pulmonary Fibrosis, Xiaoqiu Liu, Fengying Li, and Rennolds S. Ostrom
Adenylyl Cyclase Type 6 Overexpression Selectively Enhances ß-Adrenergic and Prostacyclin Receptor Mediated Inhibition of Rat Cardiac Fibroblast Function Due to Co-Localization in Lipid Rafts, Xiaoqiu Liu, Muthusamy Thangavel, Shu Qiang Sun, Joseph Kaminsky, Penden Mahautmr, Jeremiah Stitham, John Hwa, and Rennolds S. Ostrom
Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1, Surya M. Nauli, Yoshifumi Kawanabe, John J. Kaminski, William J. Pearce, Donald E. Ingber, and Jing Zhou
An Orphan GCPR Finds a Home in the Heart. Focus On “Myocardial Expression, Signaling and Function of GPR22; a Protective Role for an Orphan G Protein-Coupled Receptor”, Hemal H. Patel and Rennolds S. Ostrom
Synthesis and In Vitro Characterization of Novel Dextran- Methylprednisolone Conjugates with Peptide Linkers: Effects of Linker Length on Hydrolytic and Enzymatic Release of Methylprednisolone and Its Peptidyl Intermediates, Suman Penugonda, Anil Kumar, Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar
Assessing the Efficiency of Hospital Pharmacy Services in Thai Public District Hospitals, Thananan Rattanachotphanit, Chulaporn Limwattananon, Supon Limwattananon, Jeff R. Johns, Jon C. Schommer, and Lawrence M. Brown
Work Profiles Identified from the 2007 Pharmacist and Pharmaceutical Scientist Career Pathway Profile Survey, Jon C. Schommer, Lawrence M. Brown, and Elliott M. Sogol
Drug Selection and Adverse Drug Reactions: Balancing Outcomes and Costs, Enrique Seoane-Vazquez
Incentives for Orphan Drug Research and Development in the United States, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio, Sheryl L. Szeinbach, and Jay Visaria
Proteomic Analysis Detects Cytoskeletal-Related Proteins That Interact With the Intracellular C1 Domain of Adenylyl Cyclase 6, Muthusamy Thangavel, Xiaoqiu Liu, and Rennolds S. Ostrom
Composites Comprising Cholesterol and Carboxymethyl Cellulose, Vuk Uskoković
Insights into Morphological Nature of Precipitation of Cholesterol, Vuk Uskoković
Nanomaterials and Nanotechnologies: Approaching the Crest of this Big Wave, Vuk Uskoković
Surface Charge Effects Involved in the Control of Stability of Sols Comprising Uniform Cholesterol Particles, Vuk Uskoković
Enzymatic Processing of Amelogenin during Continuous Crystallization of Apatite, Vuk Uskoković, M.-K. Kim, W. Li, and S. Habelitz
PDGF-Driven Proliferation, Migration, and IL8 Chemokine Secretion in Human Corneal Fibroblasts Involve JAK2-STAT3 Signaling Pathway, Neeraj Vij, Ajay Sharma, Mahesh Thakkar, Sunilima Sinha, and Rajiv R. Mohan
Apurinic/Apyrimidinic Endonuclease/Redox Effector Factor-1(APE/Ref-1): A Unique Target for the Prevention and Treatment of Human Melanoma, Sun Yang and Frank L. Meyskens
Nitric Oxide Initiates Progression of Human Melanoma via a Feedback Loop Mediated by Apurinic/Apyrimidinic Endonuclease-1/redox Factor-1, Which is Inhibited by Resveratrol, Zhen Yang, Sun Yang, Bobbye J. Misner, Rita Chiu, Feng Liu, and Frank L. Meyskens Jr.
Pharmacodynamic Activity of Ertapenem versus Multidrug-Resistant Genotypically Characterized Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Using an In Vitro Model, George G. Zhanel, Patricia Baudry, Vibhu Vashisht, Nancy Laing, Ayman M. Noreddin, and Daryl J. Hoban
Submissions from 2007
Protein Pyrophosphorylation by Inositol Pyrophosphates is a Posttranslational Event, Rashna Bhandari, Adolfo Saiardi, Yousef Ahmadibeni, Adele M. Snowman, Adam C. Resnick, Troels Z. Kristiansen, Henrik Molina, Akhilesh Pandey, J. Kent Werner Jr., Krishna R. Juluri, Yong Xu, Glenn D. Prestwich, Keykavous Parang, and Solomon H. Snyder
Synthesis And Antifungal Properties Of Alpha-Methoxy And Alpha-Hydroxyl Substituted 4-Thiatetradecanoic Acids, Nestor Carballeira, Rosann O'Neill, and Keykavous Parang
Effects of Methylprednisolone and Its Liver-Targeted Dextran Prodrug on Ischemia–Reperfusion Injury in a Rat Liver Transplantation Model, Anjaneya Chimalakonda and Reza Mehvar
Antagonism of p66shc by Melanoma Inhibitory Activity, K. Kasuno, A. Naqvi, J. DeRicco, T. Yamamori, L. Santhanam, I. Mattagajasingh, Sun Yang, F. L. Meyskens, A.-K. Bosserhoff, and K. Irani
Improving Medication Safety in the ICU: The Pharmacist’s Role, Audrey J. Lee, Teresa B. Chiao, Jerika T. Lam, Shamima Khan, and Maureen S. Boro
Expression and Localization of Adenylyl Cyclases and G Protein Receptors in Guinea Pig Ileum Caveolae and Lipid Rafts, Richard Reece, Xiaoqiu Liu, Shu Q. Sun, Frederick J. Ehlert, and Rennolds S. Ostrom
The Proximal Segments of the Cytosolic Domain of Adenylyl Cyclase Type 6 Localize to Plasma Membrane Lipid Rafts and Caveolae, Muthusamy Thangavel, Xiaoqiu Liu, and Rennolds S. Ostrom
Four Novel Co-Precipitation Procedures for the Synthesis of Lanthanum-Strontium Manganites, Vuk Uskoković and Miha Drofenik
Uniform Particles of Pure and Silica Coated Cholesterol, Vuk Uskoković and Egon Matijević
Drug Utilization and Cost in a Medicaid Population: A Simulation Study of Community vs. Mail Order Pharmacy, Satish Valluri, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio, and Sheryl L. Szeinbach
Fibrocystin/Polyductin, Found in the Same Protein Complex with Polycystin-2, Regulates Calcium Responses in Kidney Epithelia, Shizuan Wang, Jingjing Zhang, Surya M. Nauli, Xiaogang Li, Patrick G. Starremans, Ying Luo, Kristina A. Roberts, and Jing Zhou
Redox Effector Factor-1, Combined with Reactive Oxygen Species, Plays an Important Role in the Transformation of JB6 Cells, Sun Yang, Bobbye J. Misner, Rita J. Chiu, and Frank L. Meyskens Jr.
Common and Distinct Mechanisms of Different Redox-Active Carcinogens Involved in the Transformation of Mouse JB6P+ Cells, Sun Yang, Bobbye J. Misner, Rita Chiu, and Frank L. Meyskens Jr.
Synthesis and Evaluation of Tripodal Peptide Analogues for Cellular Delivery of Phosphopeptides, Guofeng Ye, Nguyen Hai Nam, Anil Kumar, Ali Saleh, Dinesh B. Shenoy, Mansoor M. Amiji, Xiaofeng Lin, Gongqin Sun, and Keykavous Parang
Pharmacodynamic Activity of Ertapenem versus Penicillin-Susceptible and Penicillin-Non-Susceptible Streptococcus pneumoniae Using an In Vitro Model, George G. Zhanel, Sheldon Derkatch, Nancy Laing, Ayman M. Noreddin, and Daryl J. Hoban
Submissions from 2006
The Science of Prevention Strategies, Rachel Abrishami and Jeffery A. Goad
2,6-Hexadecadiynoic Acid and 2,6-Nonadecadiynoic Acid - Novel Synthesized Acetylenic Fatty Acids as Potent Antifungal Agents, Nestor Carballeira, David Sanabria, Clarisa Cruz, Keykavous Parang, Baojie Wan, and Scott Franzblau
Attenuation of Acute Rejection in a Rat Liver Transplantation Model by a Liver-Targeted Dextran Prodrug of Methylprednisolone, Anjaneya Chimalakonda, Donald L. Montgomery, Jon A. Weidanz, Imam H. Shaik, Justin H. Nguyen, John J. Lemasters, Eiji Kobayashi, and Reza Mehvar
Immunization Update, Karl M. Hess and Jeffery A. Goad
Synthesis of Polymer-Bound 4-acetoxy-3-phenylbenzaldehyde Derivatives: Applications in Solid-Phase Organic Synthesis, Anil Kumar, Guofeng Ye, Yousef Ahmadibeni, and Keykavous Parang
Synthesis and Structure-Activity Relationships of Linear and Conformationally Constrained Peptide Analogues of CIYKYY as Src Tyrosine Kinase Inhibitors, Anil Kumar, Guofeng Ye, Yuehao Wang, Xiaofeng Lin, Gongqin Sun, and Keykavous Parang
Cost Prevention of HIV, Jerika Lam
cAMP Inhibits TGF-ß-Stimulated Collagen Synthesis via Inhibition of ERK1/2 and SMAD Signaling in Rat Cardiac Fibroblasts, Xiaoqiu Liu, Shu Qiang Sun, Avi Hassid, and Rennolds S. Ostrom
Palmitoylation at Cys 1145 in the Carboxyl Terminus of Human Type 6 Adenylyl Cyclase is Not Required for Targeting to Lipid Rafts and Caveolae, Xiaoqiu Liu, Shu Qiang Sun, and Rennolds S. Ostrom
TGFß Signaling via ERK1/2 and Smad is Inhibited by cAMP-Elevating Agents in Rat Cardiac Fibroblasts, Xiaoqiu Liu, Shu Qiang Sun, and Rennolds S. Ostrom
Estimation of Pharmacokinetic Parameters Based on the Patient-Adjusted Population Data, Reza Mehvar
Interdependency of Pharmacokinetic Parameters: A Chicken-and-Egg Problem? Not!, Reza Mehvar
Insights into the Effects of Hyperlipoproteinemia on Cyclosporine A Biodistribution and Relationship to Renal Function, Hamidreza Montazeri Aliabadi, Tara J. Spencer, Parvin Mahdipoor, Afsaneh Lavasanifar, and Dion R. Brocks
Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary Dysfunction, Surya M. Nauli, Sandro Rossetti, Robert J. Kolb, Francis J. Alenghat, Mark B. Consugar, Peter C. Harris, Donald E. Ingber, Mahmoud Loghman-Adham, and Jing Zhou
Stromal Haze, Myofibroblasts, and Surface Irregularity after PRK, Marcelo V. Netto, Rajiv R. Mohan, Sunilima Sinha, Ajay Sharma, William Dupps, and Steven E. Wilson
Effect of Prophylactic and Therapeutic Mitomycin C on Corneal Apoptosis, Cellular Proliferation, Haze, and Long-Term Keratocyte Density in Rabbits, Marcelo V. Netto, Rajiv R. Mohan, Sunilima Sinha, Ajay Sharma, Pankaj C. Gupta, and Steven E. Wilson
Caveolin-2, Rennolds S. Ostrom
Methods for the Study of Signaling Molecules in Membrane Lipid Rafts and Caveolae, Rennolds S. Ostrom and Paul A. Insel
Rapid Determination of Reduced and Oxidized Glutathione Levels Using a New Thiol-Masking Reagent and the Enzymatic Recycling Method: Application to the Rat Liver and Bile Samples, Imam H. Shaik and Reza Mehvar
Mechanism of a Solid-State Formation of La1-xSrxMnO3+δ (0 < x < 0.5) and Magnetic Characterization Thereof, Vuk Uskoković and Miha Drofenik
Synthesis of Lanthanum-Strontium Manganites by Oxalate-Precursor Co-Precipitation Methods in Solution and in Reverse Micellar Microemulsion, Vuk Uskoković and Miha Drofenik
Preparation of Silica-Coated Lanthanum-Strontium Manganite Particles with Designable Curie Point, for Application in Hyperthermia Treatments, Vuk Uskoković, Aljoša Košak, and Miha Drofenik
Silica-Coated Lanthanum-Strontium Manganites for Hyperthermia Treatments, Vuk Uskoković, Aljoša Košak, and Miha Drofenik
Selective Effects of Nitric Oxide on the Disposition of Chlorzoxazone and Dextromethorphan in Isolated Perfused Rat Livers, Ragini Vuppugalla and Reza Mehvar
Submissions from 2005
Fibrotic Lung Fibroblasts Show Blunted Inhibition by cAMP Due to Deficient cAMP Response Element-Binding Protein Phosphorylation, Xiaoqiu Liu, Shu Qiang Sun, and Rennolds S. Ostrom
Redox Regulation by Intrinsic Species and Extrinsic Nutrients in Normal and Cancer Cells, Archana Jaiswal McEligot, Sun Yang, and Frank L. Meyskens Jr.
Role of Protein Binding in Pharmacokinetics, Reza Mehvar
Mouse Cytomegalovirus M33 is Necessary and Sufficient in Virus-Induced Vascular Smooth Muscle Cell Migration, Ryan Melnychuk, Patsy Smith, Craig N. Kreklywich, Franziska Ruchti, Jennifer Totonchy, Laurel Hall, Lambert Loh, Jay A. Nelson, Susan L. Orloff, and Daniel N. Streblow
Chronic Hypoxia Modulates Relations Among Calcium, Myosin Light Chain Phosphorylation, and Force Differently in Fetal and Adult Ovine Basilar Arteries, Surya M. Nauli, James M. Williams, William T. Gerthoffer, and William J. Pearce
A Mechanism for the Formation of Nanostructured NiZn Ferrites via a Microemulsion-Assisted Precipitation Method, Vuk Uskoković and Miha Drofenik
Synthesis of Relatively Highly Magnetic Nano-Sized NiZn-Ferrite in Microemulsion at 45 oC, Vuk Uskoković and Miha Drofenik
Synthesis of Lanthanum-Strontium Magnanites by a Hydroxide-Precursor Co-Precipitation Method in Solution and in Reverse Micellar Microemulsion, Vuk Uskoković, Darko Makovec, and Miha Drofenik