This is a central hub for research, scholarship, and creative activity on COVID-19 created by faculty, staff, and students of Chapman University.

To learn how to include your work, please email the Coordinator of Scholarly Communications & Electronic Resources, Kristin Laughtin-Dunker, at laughtin@chapman.edu.

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Submissions from 2024

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State Capacity and COVID-19 Responses: Comparing the US States, Kiran Auerbach, Joshua Y. Lerner, and Hannah M. Ridge

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A Multi-Year Longitudinal Study Exploring the Impact of the COVID-19 Pandemic on Students’ Familiarity and Perceptions of Active Learning, Briana Craig and Jeremy L. Hsu

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James Doti: COVID Mandates Cost Jobs But Didn’t Save Lives, Jim Doti

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Exploring Binding Pockets in the Conformational States of the SARS-CoV-2 Spike Trimers for the Screening of Allosteric Inhibitors Using Molecular Simulations and Ensemble-Based Ligand Docking, Grace Gupta and Gennady M. Verkhivker

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DNA Barcoding of Herbal Supplements on the U.S. Commercial Market Associated with the Purported Treatment of COVID-19, Calin M. Harris, Diane Y. Kim, Chevon R. Jordan, Miranda I. Miranda, and Rosalee S. Hellberg

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Impact of COVID-19 Pandemic on Emergency Department Visits for Opioid Use Disorder Across University of California Health Centers, Matthew Heshmatipour, Ding Quan Ng, Emily Yi-Wen Truong, Jianwei Zheng, Alexandre Chan, and Yun Wang

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Impact of a Pharmacist-Led HCV Treatment Program at a Federally Qualified Health Center, Jerika T. Lam and Sharon Xavioer

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Changes in Real-world Dispensing of ADHD Stimulants in Youth from 2019 to 2021 in California, Anika Patel, Rishikesh Chavan, Cyril Rakovski, Richard C. Beuttler, and Sun Yang

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AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN.1, KP.2 and KP.3 Variants: Mutational Profiling of Binding Energetics Reveals Epistatic Drivers of the ACE2 Affinity and Escape Hotspots of Antibody Resistance, Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta, and Gennady M. Verkhivker

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Ensemble-Based Mutational Profiling and Network Analysis of the SARS-CoV-2 Spike Omicron XBB Lineages for Interactions with the ACE2 Receptor and Antibodies: Cooperation of Binding Hotspots in Mediating Epistatic Couplings Underlies Binding Mechanism and Immune Escape, Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta, and Gennady M. Verkhivker

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Real-World Dispensing of Buprenorphine in California During Prepandemic and Pandemic Periods, Yun Wang, Alexandre Chan, Richard Beuttler, Marc L. Fleming, Todd Schneberk, Michael Nichol, and Haibing Lu

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Taming the Cytokine Storm: Small Molecule Inhibitors Targeting IL-6/IL-6α Receptor, Komal Zia, Mohammad Nur-e-Alam, Aftab Ahmed, and Zaheer Ul-Haq

Dissertations from 2023

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Computational Analysis of Antibody Binding Mechanisms to the Omicron RBD of SARS-CoV-2 Spike Protein: Identification of Epitopes and Hotspots for Developing Effective Therapeutic Strategies, Mohammed Alshahrani

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Comparative Analysis of Conformational Dynamics and Systematic Characterization of Cryptic Pockets in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB.1 Spike Complexes with the ACE2 Host Receptor: Confluence of Binding and Structural Plasticity in Mediating Networks of Conserved Allosteric Sites, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao, and Gennady M. Verkhivker

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Manufacturing Growth is Moderating, Anderson Center for Economic Research

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The Hi-Tech Industries Push the Manufacturing Sector Down, Anderson Center for Economic Research

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Virtual and In Vitro Screening of Natural Products Identifies Indole and Benzene Derivatives as Inhibitors of SARS-CoV-2 Main Protease (Mpro), Dony Ang, Riley Kendall, and Hagop S. Atamian

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Shot Talk: Development and Pilot Test of a Theory of Planned Behavior Campaign to Combat College Student COVID-19 Vaccine Hesitancy, Hannah Ball, Tayah Renea Wozniak, and Cailin M. Kuchenbecker

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Investigating Interactive Methods in Remote Chestfeeding Support for Lactation Consulting Professionals in Brazil, Jessica de Souza, Cinthia Calsinski, Kristina Chamberlain, Franceli L. Cibrian, and Edward Jay Wang

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3rd Place Contest Entry: Using the Scientific Method to Combat the Biological and Sociological Effects of the COVID-19 Pandemic: An Aspiring Healthcare Professional’s Perspective, Isabelle Dhindsa

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Using the Scientific Method to Combat the Biological and Sociological Effects of the COVID-19 Pandemic: An Aspiring Healthcare Professional’s Perspective, Isabelle Dhindsa

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Engagement in Diverse Sexual Behaviors and Desire for Different Types of Relationships Among Single Heterosexual People when COVID-19 Vaccines were First Available, Manya Dhupar, Emily Foster, Amanda Gesselman, and Justin Garcia

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The Impact of Vaccinations and Chronic Disease on COVID Death Rates, James L. Doti

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Positive Changes in Safety Perception Among Blacks with HIV and Comorbidities: Assessment of Social Determinants of Health During COVID‑19, Marc Fleming, Deidra Lee, Chukwuezugo Oranu, Jon C. Schommer, Jennifer M. Cocohoba, Jennifer Cooper, Crystal K. Hodge, Saharnaz Nedjat, and Kathleen Borgmann

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Implementation of Post-COVID Conditions Management Utilizing Interprofessional Collaboration in a Multi-facility Healthcare Organization, Jocelin Friedman, Christina Dhesi-Bawa, Kathleen Kennedy, Stephen Lee, and Leona Hidalgo

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Not a Waste: Wastewater Surveillance to Enhance Public Health, Anna Gitter, Jeremiah Oghuan, Anuja Rajendra Godbole, Carlos A. Chavarria, Carlos Monserrat, Tao Hu, Yun Wang, Anthony W. Maresso, Blake M. Hanson, Kristina D. Mena, and Fuqing Wu

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Computational Molecular Docking Studies of Small Molecule Inhibitors With the SARS-CoV-2 Spike Protein Variants: In-Silico Drug Discovery Using Virtual Screening and Drug Repurposing Approaches, Grace Gupta

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DNA Barcoding of Ayurvedic Herbal Supplements used for the Purported Treatment of COVID-19, Calin Harris

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Labeling Compliance and Online Claims for Ayurvedic Herbal Supplements on the U.S. Market Associated with the Purported Treatment of COVID-19, Chevon R. Jordan, Calin M. Harris, Miranda I. Miranda, Diane Y. Kim, and Rosalee S. Hellberg

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Labeling Compliance and Online Claims for Ayurvedic Herbal Supplements on the U.S. Market Associated with the Purported Treatment of COVID-19, Chevon R. Jordan, Calin M. Harris, Miranda I. Miranda, Diane Y. Kim, and Rosalee S. Hellberg

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Metapopulation Dynamics of SARS-CoV-2 Transmission in a Small-scale Amazonian Society, Thomas Kraft, Edmond Seabright, Sarah Alami, Samuel M. Jenness, Paul L. Hooper, Bret Beheim, Helen Davis, Daniel K. Cummings, Daniel Eid Rodriguez, Maguin Gutierrez Cayuba, Emily J. Miner, Xavier de Lamballerie, Lucia Inchauste, Stéphane Priet, Benjamin Trumble, Jonathan Stieglitz, Hillard Kaplan, and Michael Gurven

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Museums, COVID-19 and the Pivot to Social Media, Jamie Larkin, Andrea Ballatore, and Ekaterina Mityrova

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Experiences of COVID-19-Related Racism and Impact on Depression Trajectories Among Racially/Ethnically Minoritized Adolescents, Sabrina R. Liu, Elysia Poggi Davis, Anton M. Palma, Hal S. Stern, Curt A. Sandman, and Laura M. Glynn

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A Theory of the COVID-19 Pandemic’s Impact on the Government-Citizen Relationship / Teorija vpliva pandemije COVID-19 na odnos med vlado in državljani, Lewis Luartz

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Editors’ Introduction, Aurora Matzke, Louis M. Maraj, Angela Clark-Oates, Anyssa Gonzalez, and Sherry Rankins-Robertson

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Factors Affecting Initiation and Retention of Medication-Assisted Recovery (MAR) within a Pilot Pharmacist-Involved Practice Model at a Federally Qualified Healthcare Center (FQHC) during the COVID-19 Pandemic, Tiffany Nguyen, Thomas Craig Cheetham, Souhiela Fawaz, Richard Beuttler, and Sharon Xavioer

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Trigger Warnings and a Pedagogy of Trust, Morgan Read-Davidson

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COVID-Dynamic: A Large-Scale Longitudinal Study of Socioemotional and Behavioral Change Across the Pandemic, Tessa Rusch, Yanting Han, Dehua Liang, Amber R. Hopkins, Carolyn V. Lawrence, Uri Maoz, Lynn K. Paul, Damian A. Stanley, and The COVID-Dynamic Team

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Reconnecting with Exes and Having Sex with Platonic Roommates During the First Five Months of the COVID - 19 Pandemic, Valentyna Simon, Alex Kraft, Amanda Gesselman, and Justin Garcia

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Balancing Functional Tradeoffs between Protein Stability and ACE2 Binding in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB Lineages: Dynamics-Based Network Models Reveal Epistatic Effects Modulating Compensatory Dynamic and Energetic Changes, Gennady M. Verkhivker, Mohammed Alshahrani, and Grace Gupta

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Coarse-Grained Molecular Simulations and Ensemble-Based Mutational Profiling of Protein Stability in the Different Functional Forms of the SARS-CoV-2 Spike Trimers: Balancing Stability and Adaptability in BA.1, BA.2 and BA.2.75 Variants, Gennady M. Verkhivker, Mohammed Alshahrani, and Grace Gupta

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Exploring Conformational Landscapes and Cryptic Binding Pockets in Distinct Functional States of the SARS-CoV-2 Omicron BA.1 and BA.2 Trimers: Mutation-Induced Modulation of Protein Dynamics and Network-Guided Prediction of Variant-Specific Allosteric Binding Sites, Gennady M. Verkhivker, Mohammed Alshahrani, and Grace Gupta

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What Quantifies Good Primary Care in the United States? A Review of Algorithms and Metrics Using Real-World Data, Yun Wang, Jianwei Zheng, Todd Schneberk, Yu Ke, Alexandre Chan, Tao Hu, Jerika Lam, Mary Gutierrez, Ivan Portillo, Dan Wu, Chi-Hung Chang, Yang Qu, Lawrence Brown, and Michael B. Nichol

Submissions from 2022

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The Use of Advanced Spectral Imaging to Reveal Nanoparticle Identity in Biological Samples, Qamar A. Alshammari, Rajasekharreddy Pala, Ayan K. Barui, Saud O. Alshammari, Andromeda M. Nauli, Nir Katzir, Ashraf M. Mohieldin, and Surya M. Nauli

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California's Manufacturing Sector Grows for the Seventh Consecutive Quarter, Anderson Center for Economic Research

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Manufacturing Sector's Growth Rate Inches Upward, Anderson Center for Economic Research

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Manufacturing Sector Sustains Its Growth Path, Anderson Center for Economic Research

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A Descriptive Literature Review of Early Research on COVID-19 and Close Relationships, Jennifer L. Bevan, Madison K. Murphy, Pamela J. Lannutti, Richard B. Slatcher, and Rhonda N. Balzarini

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Global Cancer Statistics 2022: The Trends Projection Analysis, Bhupender S. Chhikara and Keykavous Parang

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Individual Difference Predictors of Starting a New Romantic Relationship During the COVID-19 Pandemic, Wiliam J. Chopik, Amy Moors, Daniel J. Litman, Megan S. Shuck, Alexandra R. Stapleton, Meghan C. Abrom, Kayla A. Stevenson, Jeewon Oh, and Mariah F. Purol

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High-Yield Webinar Engagement Strategies and Teacher Candidate Professional Learning, Meghan Cosier, Sara Morgan, and Audri Sandoval Gomez

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“This Isn’t Just Busy, This is Scary”: Stress, Social Support, and Coping Experiences of Frontline Nurses During the COVID-19 Pandemic, Erin S. Craw, Tess M. Buckley, and Michelle Miller-Day

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Citizenship Matters: Non-Citizen COVID-19 Mortality Disparities in New York and Los Angeles, Jason A. Douglas, Georgiana Bostean, Angel Miles Nash, Emmanuel B. John, Lawrence M. Brown, and Andrew M. Subica

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Influenza Activity and Vaccine Effectiveness During the 2021-2022 Season, Jeff Goad

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How the COVID-19 Pandemic Continues to Shape Immunization in Pharmacy, Jeffery Goad

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Editorial: Education Leadership and the COVID-19 Crisis, Margaret Grogan, Michelle D. Young, and Mónica Byrne-Jiménez

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Biophysical Insight into the SARS-CoV2 Spike–ACE2 Interaction and Its Modulation by Hepcidin through a Multifaceted Computational Approach, Hamid Hadi-Alijanvand, Luisa Di Paola, Guang Hu, David M. Leitner, Gennady M. Verkhivker, Peixin Sun, Humanath Poudel, and Alessandro Giuliani

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Online Dating During the COVID-19 Pandemic: Is it the New Norm?, Sara Henry, Emily Foster, Alexandra Kraft, and Amanda N. Gesselman

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Characterizing First-Year Biology Majors’ Motivations and Perceptions of the Discipline, Jeremy L. Hsu and Lauren Dudley

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The U.S. Travel Health Pharmacists’ Role in a Post-COVID-19 Pandemic Era, Keri Hurley-Kim, Karina Babish, Eva Chen, Alexis Diaz, Nathan Hahn, Derek Evans, Sheila M. Seed, and Karl Hess

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Teaching in the Age of Covid-19—The New Normal, Petar Jandrić, Ana Fuentes Martinez, Charles Reitz, Liz Jackson, Dennis Grauslund, David Hayes, Happiness Onesmo Lukoko, Michael Hogan, Peter Mozelius, Janine Aldous Arantes, Paul Levinson, Jānis John Ozoliņš, James D. Kirylo, Paul R. Carr, Nina Hood, Marek Tesar, Sean Sturm, Sandra Abegglen, Tom Burns, Sandra Sinfield, Georgina Tuari Stewart, Juha Suoranta, Jimmy Jaldemark, Ulrika Gustafsson, Lilia D. Monzó, Ivana Batarelo Kokić, Jimmy Ezekiel Kihwele, Jake Wright, Pallavi Kishore, Paul Alexander Stewart, Susan Bridges, Mikkel Lodahl, Peter Bryant, Kulpreet Kaur, Stephanie Hollings, James Benedict Brown, Anne Steketee, Paul Prinsloo, Moses Kayade Hazzan, Michael Jopling, Julia Mañero, Andrew Gibbons, Sarah Pfohl, Niklas Humble, Jacob Davidsen, Derek R. Ford, Navreeti Sharma, Kevin Stockbridge, Olli Pyyhtinen, Carlos Escaño, Charlotte Achieng-Evensen, Jennifer Rose, Jones Irwin, Richa Shukla, Suzanne SooHoo, Ian Truelove, Rachel Buchanan, Shreya Urvashi, E. Jayne White, Rene Novak, Thomas Ryberg, Sonja Arndt, Bridgette Redder, Mousumi Mukherjee, Blessing Funmi Komolafe, Madhav Mallya, Nesta Devine, Sahar D. Sattarzadeh, and Sarah Hayes

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COVID-19 and the State: Nicaragua Case Study, Mateo C. Jarquín Chamorro

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Extreme Development of Dragon Fruit Agriculture with Nighttime Lighting in Southern Vietnam, Shenyue Jia, Son V. Nghiem, Seung-Hee Kim, Laura Krauser, Andrea E. Gaughan, Forest R. Stevens, Menas Kafatos, and Khanh D. Ngo

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If a Tree Falls in the Forest: Presidential Press Conferences and Early Media Narratives about the COVID-19 Crisis, Masha Krupenkin, Kai Zhu, Dylan Walker, and David Rothschild

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Extending Psychological Reactance Theory to Include Denial of Threat and Media Sharing Intentions as Freedom Restoration Behavior, Noel H. McGuire and Hannah Ball

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Effects of Transcranial Direct Current Stimulation on Adults with Post-Acute COVID-19 Syndrome, Isaac Min and Aaron Schurger

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Engagement in Consensual Non-monogamy and Multi-partner Sex During the COVID-19 Pandemic: Insights From a National Sample of Single Americans, Kaylie Posen, Manya Dhupar, and Amanda Gesselman

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Clinical Skills Development in the Virtual Learning Environment: Adapting to a New World, Erini S. Serag-Bolos, Liza Barbarello Andrews, Jennifer Beall, Kelly A. Lempicki, Aimon C. Miranda, Carol Motycka, Chelsea Phillips Renfro, Brittany L. Riley, Chasity M. Shelton, Deepti Vyas, and Kimberly Won

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The Impact of the COVID-19 Pandemic on Care Delivery and Quality of Life in Lung Cancer Surgery, Dede K. Teteh, Jovani Barajas, Betty Ferrell, Ziaoke Zhou, Loretta Erhunmwunsee, Dan J. Raz, Jae Y. Kim, and Virginia Sun

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Allosteric Determinants of the SARS-CoV-2 Spike Protein Binding with Nanobodies: Examining Mechanisms of Mutational Escape and Sensitivity of the Omicron Variant, Gennady M. Verkhivker

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Conformational Flexibility and Local Frustration in the Functional States of the SARS-CoV-2 Spike B.1.1.7 and B.1.351 Variants: Mutation-Induced Allosteric Modulation Mechanism of Functional Dynamics and Protein Stability, Gennady M. Verkhivker

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Structural and Computational Studies of the SARS-CoV-2 Spike Protein Binding Mechanisms with Nanobodies: From Structure and Dynamics to Avidity-Driven Nanobody Engineering, Gennady M. Verkhivker

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Computer Simulations and Network-Based Profiling of Binding and Allosteric Interactions of SARS-CoV-2 Spike Variant Complexes and the Host Receptor: Dissecting the Mechanistic Effects of the Delta and Omicron Mutations, Gennady M. Verkhivker, Steve Agajanian, Ryan Kassab, and Keerthi Krishnan

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Integrating Conformational Dynamics and Perturbation-Based Network Modeling for Mutational Profiling of Binding and Allostery in the SARS-CoV-2 Spike Variant Complexes with Antibodies: Balancing Local and Global Determinants of Mutational Escape Mechanisms, Gennady M. Verkhivker, Steve Agajanian, Ryan Kassab, and Keerthi Krishnan

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Probing Mechanisms of Binding and Allostery in the SARS-CoV-2 Spike Omicron Variant Complexes with the Host Receptor: Revealing Functional Roles of the Binding Hotspots in Mediating Epistatic Effects and Communication with Allosteric Pockets, Gennady M. Verkhivker, Steve Agajanian, Ryan Kassab, and Keerthi Krishnan

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Time-to-Event Modeling for Hospital Length of Stay Prediction for COVID-19 Patients, Yuxin Wen, Md. Fashiar Rahman, Yan Zhuang, Michael Pokojovy, Honglun Xu, Peter McCaffrey, Alexander Vo, Eric Walser, Scott Moen, and Tzu-Liang Bill Tseng

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Machine Learning and Protein Allostery, Sian Xiao, Gennady M. Verkhivker, and Peng Tao

Submissions from 2021

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When Peril Responds to Plague: Predatory Journal Engagement with COVID-19, Ryan M. Allen

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Protecting the University as a Physical Place in the Age of Postdigitization, Ryan M. Allen and Peter McLaren

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Why Deteriorating Relations, Xenophobia, and Safety Concerns Will Deter Chinese International Student Mobility to the United States, Ryan M. Allen and Ying Ye

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Covid 19 & Qanon: Enter the World of Conspiracies, Gianluca Allesina

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California Manufacturing Sector Grows at a Slower Rate, Anderson Center for Economic Research

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Manufacturing Index Reaches Highest Level Since the Fourth Quarter of 2005, Anderson Center for Economic Research

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Manufacturing Index Reaches Record High, Anderson Center for Economic Research

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Purchasing Managers in Manufacturing Remain Optimistic About the Sector, Anderson Center for Economic Research

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California Consumer Sentiments Posts Record Increase of 37%, Anderson Center for Economic Research and Lowe Institute of Political Economy

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Covid-19 Continues to Impact California Consumer Sentiment, Anderson Center for Economic Research and Lowe Institute of Political Economy

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Improvement in Business Conditions Pushes California Consumer Sentiment Higher, Anderson Center for Economic Research and Lowe Institute of Political Economy

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OC Consumer Sentiment Hits All-Time Low, Anderson Center for Economic Research and Lowe Institute of Political Economy

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OC Consumer Sentiment Jumps almost 10 Percent in Second Quarter, Anderson Center for Economic Research and Lowe Institute of Political Economy

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OC Consumer Sentiment Surges More Than 40%, Anderson Center for Economic Research and Lowe Institute of Political Economy

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Why Do Some Americans Resist COVID-19 Prevention Behavior? An Analysis of Issue Importance, Message Fatigue, and Reactance Regarding COVID-19 Messaging, Hannah Ball and Tayah Renea Wozniak

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The Efficiency of U.S. Public Space Utilization During the COVID-19 Pandemic, Seth G. Benzell, Avinash Collis, and Christos Nicolaides

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Introduction to the Special Issue: Relationships in the Time of COVID-19, Jennifer L. Bevan and Pamela J. Lannutti

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A New Golden Age in International Higher Education: Challenges and Successes during the Pandemic and Beyond, Krishna Bista, Ryan M. Allen, and Roy Y. Chan

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Negative Shocks Predict Change in Cognitive Function and Preferences: Assessing the Negative Affect and Stress Hypothesis, Francesco Bogliacino, Cristiano Codagnone, Felipe Montealegre, Frans Folkvord, Camilo Gómez, Rafael Charris, Giovanni Liva, Francisco Lupiáñez-Villanueva, and Giuseppe A. Veltri

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America's Declining Trust In Government, Megane Bos

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Impact of COVID 19 on Library Services in US Pharmacy Programs, Sherrill Brown, Julie Kalabalik Hoganson, and Ivan Portillo

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The Economic Impact of Lockdowns: A Theoretical Assessment, Gabriele Camera and Alessandro Gioffré

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The Impact of Public Health Messaging and Personal Experience on the Acceptance of Mask Wearing During the COVID-19 Pandemic, Todd L. Cherry, Alexander G. James, and James J. Murphy