Document Type
Article
Publication Date
6-16-2024
Abstract
In this paper, we introduce the numerical strategy for mixed uncertainty propagation based on probability and Dempster–Shafer theories, and apply it to the computational model of peristalsis in a heart-pumping system. Specifically, the stochastic uncertainty in the system is represented with random variables while epistemic uncertainty is represented using non-probabilistic uncertain variables with belief functions. The mixed uncertainty is propagated through the system, resulting in the uncertainty in the chosen quantities of interest (QoI, such as flow volume, cost of transport and work). With the introduced numerical method, the uncertainty in the statistics of QoIs will be represented using belief functions. With three representative probability distributions consistent with the belief structure, global sensitivity analysis has also been implemented to identify important uncertain factors and the results have been compared between different peristalsis models. To reduce the computational cost, physics constrained generalized polynomial chaos method is adopted to construct cheaper surrogates as approximations for the full simulation.
Recommended Citation
He, Y., Battista, N.A. & Waldrop, L.D. Mixed uncertainty analysis on pumping by peristaltic hearts using Dempster–Shafer theory. J. Math. Biol. 89, 13 (2024). https://doi.org/10.1007/s00285-024-02116-6
Copyright
Springer
Included in
Biology Commons, Cardiovascular System Commons, Other Computer Sciences Commons, Other Mathematics Commons
Comments
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Journal of Mathematical Biology, volume 89, in 2024 following peer review. The final publication may differ and is available at Springer via https://doi.org/
A free-to-read copy of the final published article is available here.