The Renaissance of Aminoacyl-tRNA Synthesis

Authors

Michael Ibba, Chapman UniversityFollow
Dieter Söll, Yale University

Document Type

Article

Publication Date

5-1-2001

Abstract

The role of tRNA as the adaptor in protein synthesis has held an enduring fascination for molecular biologists. Over four decades of study, taking in numerous milestones in molecular biology, led to what was widely held to be a fairly complete picture of how tRNAs and amino acids are paired prior to protein synthesis. However, recent developments in genomics and structural biology have revealed an unexpected array of new enzymes, pathways and mechanisms involved in aminoacyl‐tRNA synthesis. As a more complete picture of aminoacyl‐tRNA synthesis now begins to emerge, the high degree of evolutionary diversity in this universal and essential process is becoming clearer.

Comments

This article was originally published in EMBO Reports, volume 2, in 2001. https://doi.org/10.1093/embo-reports/kve095

Recommended Citation

Ibba, M. and Söll, D. (2001) The renaissance of aminoacyl-tRNA synthesis. EMBO Reports 2, 382-387. https://doi.org/10.1093/embo-reports/kve095

Copyright

European Molecular Biology Organization