Genetic Code: Introducing Pyrrolysine

Authors

Michael Ibba, Chapman UniversityFollow
Dieter Söll, Yale University

Document Type

Article

Publication Date

7-17-2002

Abstract

Monomethylamine methyltransferase of the archaebacterium Methanosarcina barkeri contains a novel amino acid, pyrrolysine, encoded by the termination codon UAG. Initial studies suggest that pyrrolysine may be co-translationally inserted during protein synthesis, probably by a mechanism analogous to that operating during selenocysteine incorporation.

Comments

This article was originally published in Current Biology, volume 12, in 2002. https://doi.org/10.1016/S0960-9822(02)00947-8

Recommended Citation

Ibba, M. and Söll, D. (2002) Genetic code: introducing pyrrolysine. Curr. Biol. 12, R464-R466. https://doi.org/10.1016/S0960-9822(02)00947-8

Copyright

Elsevier