Document Type
Article
Publication Date
2016
Abstract
Bilateral renal cyst formation is the main feature of autosomal dominant polycystic kidney disease (ADPKD). We and other laboratories have previously shown that cystlining epithelia of kidneys from ADPKD patients are characterized by polyploidy. In this report, we show that endothelia from the renal capillary beds of two ADPKD patients are also polyploidy. Spectral karyotyping study further confirms our flow cytometry analyses. We suggest that polyploidy may be used as a potential cellular marker in ADPKD.
Recommended Citation
Kathem SH, AbouAlaiwi WA, Zi X, Nauli SM. Capillary endothelia from two ADPKD patients are polyploidy. Ann Clin Cytol Pathol. 2016; 2(2): 1022.
Copyright
The authors
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Included in
Cardiovascular System Commons, Endocrine System Commons, Medical Genetics Commons, Other Pharmacy and Pharmaceutical Sciences Commons, Pharmaceutics and Drug Design Commons
Comments
This article was originally published in Annals of Clinical Cytology and Pathology, volume 2, issue 2, in 2016. DOI: