Effect of Tyrosine on the Productivity of PC12 Cells by Measuring Extracellular ATP release

Authors

Sabrina Burkholder, Chapman UniversityFollow
Mary Rapmund, Chapman UniversityFollow
David Fogel, Chapman UniversityFollow
Jon Flees, Chapman UniversityFollow

Document Type

Poster

Publication Date

Spring 5-2019

Faculty Advisor(s)

Dr. Rennolds Ostrom

Abstract

Given the challenge to “reverse-engineer the brain”, our group tried to address the problems of a lack of long term focus and attention span. Tyrosine was determined to aid in mental focus and brain productivity as it is a precursor to the neurotransmitter Dopamine. Given that Tyrosine is naturally occurring in the body, it is preferable to add to the body, whereas a substance like Adderall has negative effects, including increased heart rate that, over time, can cause cardiovascular damage. Drawing connections between in increase ATP and an increased ability to focus and perform under stress, extracellular ATP secretion of PC12 cells is measured using a luminometer. This research is novel and important as it attempts to find a way to increase the human brain’s ability to focus. Based on results, higher levels of tyrosine in the brain would lead to increase overall human cognitive function and productivity

Comments

Presented at the Spring 2019 Student Scholar Symposium at Chapman University.

Recommended Citation

Burkholder, Sabrina; Rapmund, Mary; Fogel, David; and Flees, Jon, "Effect of Tyrosine on the Productivity of PC12 Cells by Measuring Extracellular ATP release" (2019). Student Scholar Symposium Abstracts and Posters. 320.
https://digitalcommons.chapman.edu/cusrd_abstracts/320