Sixty-one codons specify 20 amino acids, offering cells many options for encoding a polypeptide sequence. Two new studies (Cannarrozzi et al., 2010, Tuller et al., 2010) now foster the idea that patterns of codon usage can control ribosome speed, fine-tuning translation to increase the efficiency of protein synthesis.
Fredrick, K. and Ibba, M. (2010) How the sequence of a gene can tune its translation. Cell 141, 227-229. https://doi.org10.1016/j.cell.2010.03.033
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