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"In [1] it is claimed that, based on radiation emission measurements described in [2], a certain 'variant' of the Orch OR theory has been refuted. I agree with this claim. However, the significance of this result for Orch OR per se is unclear. After all, the refuted 'variant' was never advocated by anyone, and it contradicts the views of Hameroff and Penrose (hereafter: HP) who invented Orch OR [3].

My aim is to get clear on this situation. I argue that it is indeed reasonable to speak of 'variants' here. Orch OR is not a complete model of reality but a work in progress."


This is a pre-copy-editing, author-produced PDF of an invited comment accepted for publication in Physics of Life Reviews , volume 44, in 2023. This version may not exactly replicate the final published version. The definitive publisher-authenticated version is available online at



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