Below is a selection of dissertations from the Doctor of Philosophy in Pharmaceutical Sciences program in the School of Pharmacy.

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Dissertations from 2023

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The Structural Characterization and Bioactivity Assessment of Nonspecific Lipid Transfer Protein 1 (nsLTP1) from Caraway (Carum Carvi) Seeds, Taibah Aldakhil

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Influences of Host Cytokine Signaling on KSHV Infection in Tonsil-derived B Lymphocytes, Nedaa Alomari

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Authorizations, Prices, and Labeling Differences of Therapeutic Biologics Marketed in the United States and Saudi Arabia, Turki Altowairgi

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The Role of Cytochrome P450 2E1 in Hepatic Ischemia Reperfusion Injury and Reactive Oxygen Species Formation, Nouf Alwadei

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PRG4/CD44/PP2A Signaling Axis: A Significant Regulator of Gout Arthritis, Sandy ElSayed

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An Economic and Regulatory Analysis of Gene Therapy Products Authorized by the US Food and Drug Administration and the European Medicines Agency, Buthainah Ghanem

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An Analysis of Trends of Generic Drugs and Biologic Prices in the U.S., Mohammed Jamjoom

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Genetic Mutations of KCa2.3 and KCa3.1 Channels Affect Ca2+ Sensitivity, Razan Orfali

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Pharmacological and Pharmacokinetic Studies of a KCa2.2 Positive Allosteric Modulator, Mohammad Asikur Rahman

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Application of Informatics Tools to Facilitate the Practice of Precision Medicine with Genomic Testing and Clinical Data, Michael Sayer

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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus, Judy Weng

Dissertations from 2022

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The Use of Spectral Imaging to Reveal Inorganics and Organics Identity in The Biological Samples, Qamar Alshammari

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Cytotoxic Activity of Non-Specific Lipid Transfer Protein (nsLTP1) and Proteomic Evaluation of Heparin-Binding Proteins from Ajwain (Trachyspermum ammi) Seeds, Saud Alshammari

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Orphan Drugs: Designations, Approvals, and Prices in the US, Hana Althobaiti

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Heart in Polycystic Kidney Disease is Characterized by Cardiac Dysfunction and Structural Deformation, Farideh Amirrad

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Identifying a Glucocorticoid-activated GPCR that Rapidly and Non-Genomically Increases cAMP Levels in Mammalian Cells, Francisco Nunez

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An Exploration of Ambulatory Visits and Medications Prescribed for Patients Diagnosed with Lupus Erythematosus in the United States, Salena Marie Preciado

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Synthesis, Characterization, and Evaluation of Amphiphilic Cell-Penetrating Peptides as siRNA Delivery Tools for Cancer Therapy, Muhammad Imran Sajid

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Targeting Neuronal Nitric Oxide Synthase (nNOS) for Melanoma Treatment, Shirley Tong

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Amphiphilic Cyclic Cell-Penetrating Peptides Containing Tryptophan and Arginine as Anticancer Agents and Drug Delivery System, Khalid Zoghebi

Dissertations from 2021

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KSHV Susceptibility and Transmission Within Tonsillar Specimens, Farizeh Aalam

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Structural Characterization and in vitro Antiproliferative Activity of Non-Specific Lipid Transfer Protein 1 (nsLTP1) from Fennel (Foeniculum vulgare) Seeds, Mekdes Megeressa

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Viral Factors Influencing Early Infection Events During Ex-Vivo KSHV Infection, Ramina Nabiee

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Design and Sythesis of Conjugages of Amphiphilic Cell-Penetrating Peptides Containing Anticancer Drug and Ligand for Extra Cellular Matrix Biomarker to Provide Efficient Tumor-Targeting, Shang Eun Park

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Synovial Fibrosis in Osteoarthritis of the Knee: Mechanism of Development and Potential Therapeutic Targets, Marwa Qadri

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Development of Novel Peptide-Doxorubicin Conjugates for Targeting Triple-Negative Breast Cancer, Azam Saghaeidehkordi

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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis, Kiumars Shamloo

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Design, Synthesis, and Evaluation of a Novel Cytotoxic Peptide-Doxorubicin Conjugate Targeting Triple-Negative Breast Cancer, Elmira Ziaei

Dissertations from 2020

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Cluster Determinant 44 (CD44) Receptor and Gout: Mechanistic Role in Pathogenesis and Therapeutic Targets, Emira Bousoik

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The Roles of Primary Cilia in Cardiovascular Diseases and Cancer, Maha Jamal

Dissertations from 2019

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Amphiphilic Cell-Penetrating Hybrid Cyclic-Linear Peptides as a Drug Delivery System, Saghar Mozaffari

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Sensory Primary Cilium is a Distinct Signaling Compartment, Rinzhin Tshering Sherpa