Student Scholar Symposium Abstracts and Posters

Document Type


Publication Date

Spring 5-14-2015

Faculty Advisor(s)

Melissa Rowland-Goldsmith


The Warburg effect states that cancer cells mainly receive their energy from anaerobic glycolysis. Thus, mitochondria play a different role in the metabolism of cancer cells as opposed to normal, healthy cells. In chemotherapy, there is always a chance of the cancer regressing. Making drug-resistant cancer cells to analyze their metabolism may change how cancer is treated. This study aimed to create drug-resistant MCF-7 cell lines with doxorubicin in order to determine the metabolic changes that have occurred in the process of becoming resistant to drug treatments.


Presented at the Spring 2015 Student Research Day at Chapman University.