Whole Cell Arsenic Biosensor- A Cheap Technology for Bioavailable Arsenic (As) Determination
The threat of arsenic pollution to public health and wild life has led to an increased interest in developing systems that can monitor bioavailable arsenic in potable water. This paper reviews the principal milestones in the development of arsenic biosensor combining a selective biological recognition element (microorganism) and a sensitive transducer (microilluminator), are environmental tools applied for environmental bioavailable arsenic pollution monitoring. We have discussed here the mechanism of Arsenic intake and expression of reporter gene in the bioreporter. The bioluminescent bioreporter integrated circuit (BBIC) can be developed in which a bioreporter is engineered to luminescence when target substrate (arsenite) is encountered, while the circuit detects the luminescence and after processing the signal, the results are communicated by remote sensing. BBIC provides a low power, inexpensive, selective and highly sensitive Arsenic biosensors.
Soangra R, Majumder CB, Roy P. Whole cell arsenic biosensor-A cheap technology for bioavailable arsenic (As) determination. European Journal of Advances in Engineering and Technology. 2015;2(5):52-61.