Microgel Translocation through Pores under Confinement

Document Type

Article

Publication Date

2010

Abstract

Hydrogel microparticles can conform to and pass through pores up to 10 times smaller than the particle diameter (see picture). Network flexibility of this extent is unprecedented in the context of pore passage. Microgels even show such compressibility and prepenetration at size ratios and pressure differentials comparable to physiological renal filtration conditions, making them of potential interest in drug-delivery applications.

Comments

This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Angewandte Chemie--International Edition, volume 49, issue 12, 2010 following peer review. The definitive publisher-authenticated version is available online at DOI: 10.1002/anie.200906606.

Copyright

Wiley-VCH

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