Letter to the Editor: Demonstration of Elevated Cerebrospinal Fluid CRH Levels During Pregnancy Provides Support for (Not Against) the Link Between CRH and Postpartum Depression

Document Type

Letter to the Editor

Publication Date



"The authors interpret the high P value derived from their Student t test of case/control data as meaningful evidence of a lack of relation between CSF CRH and new-onset PPD. We urge readers to consider the alternative view that, with only 6 cases, the P value does not provide meaningful insight that would justify this interpretation."


This article was originally published in The Journal of Clinical Endocrinology & Metabolism, volume 101, issue 2, in 2016. DOI: 10.1210/jc.2015-3798


Oxford University Press