Postpartum depression (PPD) is common and has serious implications for the mother and her newborn. A possible link between placental corticotropin-releasing hormone (pCRH) and PPD incidence has been discussed, but there is a lack of empirical evidence.
Yim I, Glynn LM, Dunkel Schetter C, Hobel CJ, Chicz-DeMet A & Sandman (2009). Elevated corticotrophin-releasing hormone in human pregnancy increases the risk of postpartum depressive symptoms. Archives of General Psychiatry, 66, 162-269.
American Medical Association