An improved simple and facile synthesis of chromene derivatives by employing threecomponent one-pot condensation reaction of β-naphthol, aromatic aldehydes, and malononitrile in ionic liquids is described.
Rao, M. S., Chhikara, B. S., Tiwari, R., Nasrolahi Shirazi, A., Parang, K., Kumar, A. "Greener synthesis of 2-aminochromenes in ionic liquid and evaluation of their antiproliferative activities." Chemistry & Biology Interface (2012) 2, 362-372.
Indian Society of Chemists and Biologists