Document Type
Article
Publication Date
2010
Abstract
Crosslinked polystyrene-supported aluminum chloride (PS-AlCl3) is a stable, recyclable and environmental friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford diindolylmethanes. In addition, PS-AlCl3 shows satisfactory selectivity in the reaction of mixtures of an aldehyde and a ketone with indole. Although AlCl3 is a water sensitive, corrosive and environmentally harmful compound, PS-AlCl3 is a stable and water-tolerant species. The mild reaction conditions, short reaction times, easy work-up, high to excellent yields, chemoselectivity, reuse of the catalyst for at least ten times without significant change in its catalytic activity, low cost, and easy preparation and handling of the polymeric catalyst are obvious advantages of the present method.
Recommended Citation
Tamami, Bahman, Nasrolahi Amir Shirazi, and Parvanak Kaveh Borujeni. "Polystyrene-supported aluminum chloride as an efficient and reusable catalyst for condensation of indole with various carbonyl compounds." Journal of the Serbian Chemical Society 75.4 (2010): 423-431.
DOI:10.2998/JSC090831026T
Copyright
Serbian Chemical Society
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Comments
This article was originally published in Journal of the Serbian Chemical Society, volume 75, issue 4, in 2010. DOI: 10.2998/JSC090831026T